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Figure 1 | Molecular Cancer

Figure 1

From: Characterizing cancer cells with cancer stem cell-like features in 293T human embryonic kidney cells

Figure 1

Transplantation of 293T cells into the cleared mammary fat pad of immunocompromised mice yields serially transplanting tumors. A) Skin overlying grossly involved tumor is necrotic and abnormal and tumors demonstrate gross tumor vasculature and are diffusely positive for vascular endothelial growth factor (VEGF). B) By immunohistochemical analysis tumor xenografts are strongly vimentin positive, E-cadherin negative and beta-catenin positive at the membrane while K19, an epithelial marker is completely negative.

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