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Table 1 TLX1/NOTCH signature gene response to MYC inhibition in ALL-SIL cells

From: TLX1 and NOTCH coregulate transcription in T cell acute lymphoblastic leukemia cells

Gene Fold Downregulation
CD1B 3.6 ± 0.4
HMGA2 2.4 ± 0.3
L1TD1 5.9 ± 0.4
OR10R2 1.9 ± 0.1
PLAC8 0.5 ± 0.1
RAG1 11.1 ± 2.7
SH3BP5 1.2 ± 0.1
SLC44A1 1.5 ± 0.1
  1. Fold downregulation was defined as the ratio of the qRT-PCR values obtained for untreated cells (DMSO) versus cells treated for 2 days with 50 μM of the MYC inhibitor 10058-F4.