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Table 1 Clonagenicity of the epithelial cell lines with dnLMP1

From: Evaluation of LMP1 of Epstein-Barr virus as a therapeutic target by its inhibition

cell line

transgene

colonies per μg of DNA

colony ratio

 

status

pGFPdnLMP1

pGFP

pGFPdnLMP1:pGFP

53.217

-

164

170.4

1 : 1.0

53.234a

+

8.8

41.6

1 : 4.7

53.204

+

0

4.2

-

53.191

+

14

42

1 : 3.0

53.226b

+

1.6

6

1 : 3.8

53.278a

+

46

112

1 : 2.4

53.278b

+

1.2

13.2

1 : 11.0

  1. The various cell lines (as shown) were transfected and grown for two weeks under G418 selection before fixing and staining with crystal violet (details in the legend to figure 2). The number of colonies per μg of DNA and the ratio of colonies for the GFPdnLMP1:GFP plasmids are tabulated.