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Table 2 NB-hypo genes

From: A biology-driven approach identifies the hypoxia gene signature as a predictor of the outcome of neuroblastoma patients

Gene Name GenBank* Description Reference†
AK3L1 NM_013410 adenylate kinase 3-like 1 [14]
ALDOC NM_005165 aldolase C, fructose-bisphosphate [71]
ANGPTL4 NM_016109 angiopoietin-like 4 [72]
ANKRD37 AA886870 ankyrin repeat domain 37 [73]
BHLHB2 NM_003670 basic helix-loop-helix domain containing, class B, 2 [74]
BNIP3 NM_004052 BCL2/adenovirus E1B 19 kDa interacting protein 3 [43]
BNIP3L AF060922 BCL2/adenovirus E1B 19 kDa interacting protein 3-like [75]
BTG1 NM_001731 B-cell translocation gene 1, anti-proliferative [76]
DDIT4 NM_019058 DNA-damage-inducible transcript 4 [43]
E2IG5 NM_014367 growth and transformation-dependent protein [77]
EGLN1 BC005369 egl nine homolog 1 (C. elegans) [78]
EGLN3 NM_022073 egl nine homolog 3 (C. elegans) [79]
FUT11 BF541967 fucosyltransferase 11 (alpha (1,3) fucosyltransferase) --
IGF1R H05812 insulin-like growth factor 1 receptor [80]
IGFBP3 M31159 insulin-like growth factor binding protein 3 [81]
JMJD1A AA524505 jumonji domain containing 1A [82]
MAPT AI056359 microtubule-associated protein tau --
MTP18 AF060924 mitochondrial protein 18 kDa --
MXI1 NM_005962 MAX interactor 1; MAX interactor 1 [83]
NDRG1 NM_006096 N-myc downstream regulated gene 1 [84]
P4HA2 NM_004199 procollagen-proline, 2-oxoglutarate 4-dioxygenase, alpha polypeptide II [85]
PDK1 NM_002610 pyruvate dehydrogenase kinase, isoenzyme 1 [71]
PFKFB4 AL038787 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 [86]
PGK1 NM_000291 phosphoglycerate kinase 1 [87]
PGM1 NM_002633 phosphoglucomutase 1 [88]
PLOD1 NM_000302 procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1 [85]
SLC2A3 NM_006931 solute carrier family 2 (facilitated glucose transporter), member 3 [89]
TNIP1 NM_006058 TNFAIP3 interacting protein 1 --
TPI1 NM_000365 triosephosphate isomerase 1 [90]
TXNIP AA812232 thioredoxin interacting protein [81]
VEGF AF022375 vascular endothelial growth factor [71]
ZNF395 NM_017606 zinc finger protein 395 [91]
  1. * GenBank accession number.
  2. † Representative references for genes previously shown to be modulated by hypoxia.
  3. The genes that overlap with other hypoxia signatures are in bold.
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Molecular Cancer

ISSN: 1476-4598