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Table 5 Prognostic significance of other hypoxia signatures compared to NB-hypo

From: A biology-driven approach identifies the hypoxia gene signature as a predictor of the outcome of neuroblastoma patients

  Hypoxia metagene (Winter)[30] Hypoxia metagene (Buffa)[31] VEGF signature[32] Early hypoxia signature 0%[33] Early hypoxia signature 2%[33] NB-hypo
log-rank test* 0.006 0.945 0.891 0.225 0.414 < 0.001
P 0.248 0.827 0.649 0.012 0.636 0.007
HR 1.57 1.11 1.25 6.35 1.22 2.73
95% CI (0.73, 3.35) (0.44, 2.75) (0.47, 3.31) (1.50, 27.03) (0.54, 2.76) (1.31, 5.69)
  1. * p-value of the log-rank test for overall survival patients stratification.
  2. p-value for the multivariate Cox analysis for 88 patients.
  3. Significant p-values (p < 0.01) are in bold.