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Table 5 Prognostic significance of other hypoxia signatures compared to NB-hypo

From: A biology-driven approach identifies the hypoxia gene signature as a predictor of the outcome of neuroblastoma patients

 

Hypoxia metagene (Winter)[30]

Hypoxia metagene (Buffa)[31]

VEGF signature[32]

Early hypoxia signature 0%[33]

Early hypoxia signature 2%[33]

NB-hypo

log-rank test*

0.006

0.945

0.891

0.225

0.414

< 0.001

P†

0.248

0.827

0.649

0.012

0.636

0.007

HR

1.57

1.11

1.25

6.35

1.22

2.73

95% CI

(0.73, 3.35)

(0.44, 2.75)

(0.47, 3.31)

(1.50, 27.03)

(0.54, 2.76)

(1.31, 5.69)

  1. * p-value of the log-rank test for overall survival patients stratification.
  2. † p-value for the multivariate Cox analysis for 88 patients.
  3. Significant p-values (p < 0.01) are in bold.