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Figure 2 | Molecular Cancer

Figure 2

From: SOX11 expression correlates to promoter methylation and regulates tumor growth in hematopoietic malignancies

Figure 2

Methylation status of SOX11 promoter region correlated to SOX11 expression. Methylation status of SOX11 promoter (described as percentage of methylated CpGs of 28 possible CpG methylation sites) was analyzed by direct bisulfite sequencing (right Y-axis) and correlated to SOX11 expression on mRNA (left Y-axis) and protein level in nineteen lymphoid or monocytic cell lines (Table 1). Generally, all samples with a ΔCT (SOX11+RT, SOX11-RT) < |2| was considered negative and the RQ was set to 0.01 for those samples. RQ values are related to the SOX11 expression in GRANTA-519 and the error bars show the 95% confidence interval

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