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Figure 5 | Molecular Cancer

Figure 5

From: SOX11 expression correlates to promoter methylation and regulates tumor growth in hematopoietic malignancies

Figure 5

Overexpression of SOX11 decrease proliferation. a) mRNA expression of SOX11 at 24 h after overexpression of the SOX11 gene in six B cell lymphoma cell lines. b) Western blot analysis at 24 h confirms SOX11 overexpression in SOX11 transfected samples (right), compared to wt (left) and control vector (middle), loading control (GAPDH) is seen below c) Proliferation assay at 48 h after transfection showed decreased cell growth in all cell lines but BJAB where the decrease could be seen already after 24 h. In a) all values are relative quantity (RQ) compared to the GFP value for GRANTA 519. In c) all cell lines are compared to their respective GFP value. The data is representative of three independent assays. In a) the error bars show the 95% confidence interval, while in c) ±1SD is shown.

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