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Figure 2 | Molecular Cancer

Figure 2

From: Fusion of EML4 and ALK is associated with development of lung adenocarcinomas lacking EGFR and KRAS mutations and is correlated with ALK expression

Figure 2

ALK expression is associated with ALK fusion status. (A) ALK is overexpressed at the mRNA level in 10 fusion-positive cases analyzed using Affymetrix Genechip® U133 plus 2.0. AP, Adjacent normal tissues; N, Cancer samples with no fusion; Y, Cancer samples positive for fusion. (B) ALK is differentially expressed between EML-ALK fusion-positive and negative samples (normalized intensity of 21.99 vs. 0.45, respectively; P = 0.0018), but EML4 expression was not significantly different between the groups. Error bars indicate mean ± standard deviation.

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Molecular Cancer

ISSN: 1476-4598