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Table 1 EML4-ALK fusion variants identified in the 12 NSCLC cases.

From: Fusion of EML4 and ALK is associated with development of lung adenocarcinomas lacking EGFR and KRAS mutations and is correlated with ALK expression

Variant

Published fusion type*

No. of positive samples

Frequency

V1

EML4 E13-ALK E20

4

3.9%

V2

EML4 E20-ALK E20

1

1.0%

V3a

EML4 E6-ALK E20

3

2.9%

V3b

EML4 E6-11 aa in INS6-ALK E20

  

V4

EML4 E15-ALK E20

0

0

V5

EML4 E2-ALK E20

1

1.0%

V6

EML4 E18-ALK E20

3

2.9%

  1. *All fusion types have previously been published.
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Molecular Cancer

ISSN: 1476-4598