Figure 1From: The dietary isothiocyanate sulforaphane modulates gene expression and alternative gene splicing in a PTEN null preclinical murine model of prostate cancerHeterogeneity in PTEN and pAKT expression in non-malignant human prostate tissue. Representative examples of non-malignant human prostate tissue illustrating heterogeneity of PTEN and pAKT expression: (A) illustrates high level of nuclear and cytoplastic expression of PTEN with no pAKT expression, (B) illustrates loss of PTEN expression with enhanced pAKT expression, (C) illustrates loss of PTEN expression without apparent increase in pAKT, (D) illustrates expression of both PTEN and pAKT associated with atrophy. Bar = 100 μm.Back to article page