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Figure 10 | Molecular Cancer

Figure 10

From: The dietary isothiocyanate sulforaphane modulates gene expression and alternative gene splicing in a PTEN null preclinical murine model of prostate cancer

Figure 10

Effect of HSF on the expression of the PTEN null signature genes. A, Expression of the five week 198 PTEN signature list in PTEN null mice fed the control diet compared to WT mice fed control diet, and 5-week old PTEN null mice supplemented with HSF diet compared to WT mice fed control diet. The addition of SF results in the magnitude of change in expression of each gene being suppressed by on average 33% (see Table 1 and Additional file 1 - Table S1). B, Expression of the eight week 989 PTEN signature list in PTEN null mice fed control diet compared to WT mice fed control diet, and 8-week old PTEN null mice supplemented with HSF diet compared to WT mice fed control diet (see Table 1).The addition of SF results in the magnitude of change in expression of each gene being suppressed by on average 18%.

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