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Table 1 Changes in transcript expression in PTEN null and WT mice following SF-rich diets (LSF, HSF) and control diet (CO).

From: The dietary isothiocyanate sulforaphane modulates gene expression and alternative gene splicing in a PTEN null preclinical murine model of prostate cancer

Comparison Five weeks Eight weeks
  p < 0.11 p < 0.051 p < 0.011 p < 0.11 p < 0.051 p < 0.011
WT       
LSF vs CO 0 0 0 3 3 0
HSF vs CO 3 0 0 0 0 0
PTEN null       
LSF vs CO 17 3 0 26 12 1
HSF vs CO 2862 803 11 189 72 25
Interaction       
PTEN null CO vs WT CO 385 1984 8 1542 9895 296
PTEN null LSF vs WT CO 660 287 42 2379 17185 822
PTEN null HSF vs WT CO 15 0 0 3380 23905 1204
  1. 1 Benjamini and Hochberg adjusted P-values between the two groups.
  2. 2 Further details of these transcripts are provided in Figure 8 and Table 2.
  3. 3Human orthologues of these transcripts were identified and compared to results from a human dietary intervention study performed previously (Figure 9).
  4. 4Details of these transcripts and their expression are provided in Figure 10A and Additional file 1 - Table S1.
  5. 5Functional analyses of these transcripts are provided in Table 3, and further analyses in Figure 11.