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Table 1 GSEA of human stem cell signatures

From: Gene expression profiling of mouse p53-deficient epidermal carcinoma defines molecular determinants of human cancer malignancy

Gene Set Name (N)1

Number of enriched genes

NES

FDR q-val

ES EXP1 (315)

128

2.16

<0.0001*

ES EXP2 (32)

9

1.89

<0.0001*

MYC Targets2 (664)

182

1.63

0.0022*

SOX2 Targets (584)

166

1.54

0.0058*

MYC Targets1 (199)

55

1.47

0.013*

NANOG Targets (797)

225

1.38

0.021*

OCT4 Targets (242)

63

1.22

0.068

NOS Targets (152)

32

1.08

0.23

H3K27 BOUND (886)

245

-1.65

0.0026*

PRC2 Targets (508)

126

-1.59

0.0038*

EED Targets (800)

183

-1.55

0.0042*

SUZ12 Targets (819)

201

-1.65

0.005*

NOS TFS (32)

5

-1.08

0.24

  1. 1 N: number of genes from each gene set in mouse chip.
  2. NES: normalized enrichment score.
  3. NES > 0: enrichment in tumors; NES < 0: enrichment in normal skin.
  4. *Significant enrichment.