TY - JOUR AU - Casey, P. J. AU - Seabra, M. C. PY - 1996 DA - 1996// TI - Protein prenyltransferases JO - J Biol Chem VL - 271 UR - https://doi.org/10.1074/jbc.271.10.5289 DO - 10.1074/jbc.271.10.5289 ID - Casey1996 ER - TY - JOUR AU - Tamanoi, F. AU - Mitsuzawa, H. PY - 1995 DA - 1995// TI - Use of yeast for identification of farnesyltransferase inhibitors and for generation of mutant farnesyltransferases JO - Methods Enzymol VL - 255 UR - https://doi.org/10.1016/S0076-6879(95)55011-9 DO - 10.1016/S0076-6879(95)55011-9 ID - Tamanoi1995 ER - TY - JOUR AU - Adjei, A. A. PY - 2006 DA - 2006// TI - Farnesyltransferase inhibitors JO - Update on Cancer Therapeutics VL - 1 UR - https://doi.org/10.1016/j.uct.2006.05.005 DO - 10.1016/j.uct.2006.05.005 ID - Adjei2006 ER - TY - JOUR AU - Appels, N. M. AU - Beijnen, J. H. AU - Schellens, J. H. PY - 2005 DA - 2005// TI - Development of farnesyl transferase inhibitors: a review JO - Oncologist VL - 10 UR - https://doi.org/10.1634/theoncologist.10-8-565 DO - 10.1634/theoncologist.10-8-565 ID - Appels2005 ER - TY - JOUR AU - Basso, A. D. AU - Kirschmeier, P. AU - Bishop, W. R. PY - 2006 DA - 2006// TI - Lipid posttranslational modifications. Farnesyl transferase inhibitors JO - J Lipid Res VL - 47 UR - https://doi.org/10.1194/jlr.R500012-JLR200 DO - 10.1194/jlr.R500012-JLR200 ID - Basso2006 ER - TY - JOUR AU - Lancet, J. E. AU - Gojo, I. AU - Gotlib, J. AU - Feldman, E. J. AU - Greer, J. AU - Liesveld, J. L. AU - Bruzek, L. M. AU - Morris, L. AU - Park, Y. AU - Adjei, A. A. AU - Kaufmann, S. H. AU - Garrett-Mayer, E. AU - Greenberg, P. L. AU - Wright, J. J. AU - Karp, J. E. PY - 2007 DA - 2007// TI - A phase 2 study of the farnesyltransferase inhibitor tipifarnib in poor-risk and elderly patients with previously untreated acute myleogenous leukemia JO - Blood VL - 109 UR - https://doi.org/10.1182/blood-2006-04-014357 DO - 10.1182/blood-2006-04-014357 ID - Lancet2007 ER - TY - JOUR AU - Martin, L. A. AU - Head, J. E. AU - Pancholi, S. AU - Salter, J. AU - Quinn, E. AU - Detre, S. AU - Kaye, S. AU - Howes, A. AU - Dowsett, M. AU - Johnston, S. R. PY - 2007 DA - 2007// TI - The farnesyltransferase inhibitor R115777 (tipifarnib) in combination with tamoxifen acts synergistically to inhibit MCF-7 breast cancer cell proliferation and cell cycle progression in vitro and in vivo JO - Mol Cancer Ther VL - 6 UR - https://doi.org/10.1158/1535-7163.MCT-06-0452 DO - 10.1158/1535-7163.MCT-06-0452 ID - Martin2007 ER - TY - JOUR AU - Karp, J. E. AU - Lancet, J. E. PY - 2008 DA - 2008// TI - Tipifarnib in the treatment of newly diagnosed acute myelogenous leukemia JO - Biologics VL - 2 ID - Karp2008 ER - TY - JOUR AU - Sparano, J. A. AU - Moulder, S. AU - Kazi, A. AU - Coppola, D. AU - Negassa, A. AU - Vahdat, L. AU - Li, T. AU - Pellegrino, C. AU - Fineberg, S. AU - Munster, P. AU - Malafa, M. AU - Lee, D. AU - Hoschander, S. AU - Hopkins, U. AU - Hershman, D. AU - Wright, J. J. AU - Kleer, C. AU - Merajver, S. AU - Sebti, S. M. PY - 2009 DA - 2009// TI - Phase II trial of tipifarnib plus neoadjuvant doxorubicin-cyclophosphamide in patients with clinical stage IIB-IIIC breast cancer JO - Clin Cancer Res VL - 15 UR - https://doi.org/10.1158/1078-0432.CCR-08-2658 DO - 10.1158/1078-0432.CCR-08-2658 ID - Sparano2009 ER - TY - JOUR AU - Kho, Y. AU - Kim, S. C. AU - Jiang, C. AU - Barma, D. AU - Kwon, S. W. AU - Cheng, J. AU - Jaunbergs, J. AU - Weinbaum, C. AU - Tamanoi, F. AU - Falck, J. AU - Zhao, Y. PY - 2004 DA - 2004// TI - A tagging-via-substrate technology for detections and proteomics of farnesylated proteins JO - Proc Natl Acad Sci VL - 101 UR - https://doi.org/10.1073/pnas.0403413101 DO - 10.1073/pnas.0403413101 ID - Kho2004 ER - TY - JOUR AU - Ashar, H. R. AU - James, L. AU - Gray, K. AU - Carr, D. AU - Black, S. AU - Armstrong, L. AU - Bishop, W. R. AU - Kirschmeier, P. PY - 2000 DA - 2000// TI - Farnesyl transferase inhibitors block the farnesylation of CENP-E and CENP-F and alter the association of CENP-E with the microtubules JO - J Biol Chem VL - 275 UR - https://doi.org/10.1074/jbc.M003469200 DO - 10.1074/jbc.M003469200 ID - Ashar2000 ER - TY - JOUR AU - Crespo, N. C. AU - Ohkanda, J. AU - Yen, T. J. AU - Hamilton, A. D. AU - Sebti, S. M. PY - 2001 DA - 2001// TI - The farnesyltransferase inhibitor, FTI-2153 blocks bipolar spindle formation and chromosome alignement and causes prometaphase accumulation during mitosis of human lung cancer cells JO - J Biol Chem VL - 276 UR - https://doi.org/10.1074/jbc.M006213200 DO - 10.1074/jbc.M006213200 ID - Crespo2001 ER - TY - JOUR AU - Schafer-Hales, K. AU - Iaconelli, J. AU - Snyder, J. P. AU - Prussia, A. AU - Nettles, J. H. AU - El-Naggar, A. AU - Khuri, F. R. AU - Giannakakou, P. AU - Marcus, A. I. PY - 2007 DA - 2007// TI - Farnesyl transferase inhibitors impair chromosomal maintenance in cell lines and human tumors by compromising CENP-E and CENP-F function JO - Mol Cancer Ther VL - 6 UR - https://doi.org/10.1158/1535-7163.MCT-06-0703 DO - 10.1158/1535-7163.MCT-06-0703 ID - Schafer-Hales2007 ER - TY - JOUR AU - Zujewski, J. AU - Horak, I. D. AU - Bol, C. J. AU - Woestenborghs, R. AU - Bowden, C. AU - End, D. W. AU - Piotrovsky, V. K. AU - Chiao, J. AU - Belly, R. T. AU - Todd, A. AU - Kopp, W. C. AU - Kohler, D. R. AU - Chow, C. AU - Noone, M. AU - Hakim, F. T. AU - Larkin, G. AU - Gress, R. E. AU - Nussenblatt, R. B. AU - Kremer, A. B. AU - Cowan, K. H. PY - 2000 DA - 2000// TI - Phase I and pharmacokinetic study of farnesyl protein transferase inhibitor R115777 in advanced cancer JO - J Clin Oncol VL - 18 ID - Zujewski2000 ER - TY - JOUR AU - Raponi, M. AU - Harousseau, J. L. AU - Lancet, J. E. AU - Löwenberg, B. AU - Stone, R. AU - Zhang, Y. AU - Rackoff, W. AU - Wang, Y. AU - Atkins, D. PY - 2007 DA - 2007// TI - Identification of molecular predictors of response in a study of tipifarnib treatment in relapsed and refractory acute myelogenous leukemia JO - Clin Cancer Res VL - 13 UR - https://doi.org/10.1158/1078-0432.CCR-06-2609 DO - 10.1158/1078-0432.CCR-06-2609 ID - Raponi2007 ER - TY - JOUR AU - Baetz, K. AU - McHardy, L. AU - Gable, K. AU - Tarling, T. AU - Rebérioux, D. AU - Bryan, J. AU - Andersen, R. J. AU - Dunn, T. AU - Hieter, P. AU - Roberge, M. PY - 2004 DA - 2004// TI - Yeast genome-wide drug-induced haploinsufficiency screen to determine drug mode of action JO - Proc Natl Acad Sci USA VL - 101 UR - https://doi.org/10.1073/pnas.0307122101 DO - 10.1073/pnas.0307122101 ID - Baetz2004 ER - TY - JOUR AU - Lum, P. Y. AU - Armour, C. D. AU - Stepaniants, S. B. AU - Cavet, G. AU - Wolf, M. K. AU - Butler, J. S. AU - Hinshaw, J. C. AU - Garnier, P. AU - Prestwich, G. D. AU - Leonardson, A. AU - Garrett-Engele, P. AU - Rush, C. M. AU - Bard, M. AU - Schimmack, G. AU - Phillips, J. W. AU - Roberts, C. J. AU - Shoemaker, D. D. PY - 2004 DA - 2004// TI - Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes JO - Cell VL - 116 UR - https://doi.org/10.1016/S0092-8674(03)01035-3 DO - 10.1016/S0092-8674(03)01035-3 ID - Lum2004 ER - TY - JOUR AU - Perlstein, E. O. AU - Ruderfer, D. M. AU - Roberts, D. C. AU - Schreiber, S. L. AU - Kruglyak, L. PY - 2007 DA - 2007// TI - Genetic basis of individual differences in the response to small-molecule drugs in yeast JO - Nat Genet VL - 39 UR - https://doi.org/10.1038/ng1991 DO - 10.1038/ng1991 ID - Perlstein2007 ER - TY - JOUR AU - McCue, P. P. AU - Phang, J. M. PY - 2008 DA - 2008// TI - Identification of human intracellular targets of the medicinal Herb St. John's Wort by chemical-genetic profiling in yeast JO - J Agric Food Chem VL - 56 UR - https://doi.org/10.1021/jf801593a DO - 10.1021/jf801593a ID - McCue2008 ER - TY - JOUR AU - Brunner, T. B. AU - Hahan, S. M. AU - Gupta, A. K. AU - Muschel, R. J. AU - McKenna, G. AU - Bernhard, E. J. PY - 2003 DA - 2003// TI - Farnesyltransferase Inhibitors: An Overview of the results of preclinical and Clinical Investigation JO - Cancer Res VL - 63 ID - Brunner2003 ER - TY - JOUR AU - Cox, A. D. AU - Garcia, A. M. AU - Westwick, J. K. AU - Kowalczyk, J. J. AU - Lewis, M. D. AU - Brenner, D. A. AU - Der, C. J. PY - 1994 DA - 1994// TI - The CAAX peptidomimetic compound B581 specifically blocks farnesylated, but not geranylgeranylated or myristylated, oncogenic ras signaling and transformation JO - J Biol Chem VL - 269 ID - Cox1994 ER - TY - JOUR AU - Doisneau-Sixou, S. F. AU - Cestac, P. AU - Faye, J. C. AU - Favre, G. AU - Sutherland, R. L. PY - 2003 DA - 2003// TI - Additive effects of tamoxifen and the farnesyl transferase inhibitor FTI-277 on inhibition of MCF-7 breast cancer cell-cycle progression JO - Int J Cancer VL - 106 UR - https://doi.org/10.1002/ijc.11263 DO - 10.1002/ijc.11263 ID - Doisneau-Sixou2003 ER - TY - JOUR AU - Yamaguchi, M. AU - Zhou, C. AU - Nanda, A. AU - Zhang, J. H. PY - 2004 DA - 2004// TI - Ras protein contributes to cerebral vasospasm in a canine double-hemorrhage model JO - Stroke VL - 35 UR - https://doi.org/10.1161/01.STR.0000129898.68350.9f DO - 10.1161/01.STR.0000129898.68350.9f ID - Yamaguchi2004 ER - TY - JOUR AU - Zhang, B. AU - Groffen, J. AU - Heisterkamp, N. PY - 2005 DA - 2005// TI - Resistance to farnesyltransferase inhibitors in Bcr/Abl-positive lymphoblastic leukemia by increased expression of a novel ABC transporter homolog ATP11a JO - Blood VL - 106 UR - https://doi.org/10.1182/blood-2004-09-3655 DO - 10.1182/blood-2004-09-3655 ID - Zhang2005 ER - TY - JOUR AU - Petronczki, M. AU - Siomos, M. F. AU - Nasmyth, K. PY - 2003 DA - 2003// TI - Un ménage à quatre: the molecular biology of chromosome segregation in meiosis JO - Cell VL - 112 UR - https://doi.org/10.1016/S0092-8674(03)00083-7 DO - 10.1016/S0092-8674(03)00083-7 ID - Petronczki2003 ER - TY - JOUR AU - Mamnun, Y. M. AU - Schüller, C. AU - Kuchler, K. PY - 2004 DA - 2004// TI - Expression regulation of the yeast PDR5 ATP-binding cassette (ABC) transporter suggests a role in cellular detoxification during the exponential growth phase JO - FEBS Letters VL - 559 UR - https://doi.org/10.1016/S0014-5793(04)00046-8 DO - 10.1016/S0014-5793(04)00046-8 ID - Mamnun2004 ER - TY - JOUR AU - Wang, E. AU - Casciano, C. N. AU - Clement, R. P. AU - Johnson, W. W. PY - 2001 DA - 2001// TI - The farnesyl protein transferase inhibitor SCH66336 is a potent inhibitor of MDR1 product P-glycoprotein JO - Cancer Res VL - 61 ID - Wang2001 ER - TY - JOUR AU - Katayama, K. AU - Yoshioka, S. AU - Tsukahara, S. AU - Mitsuhashi, J. AU - Sugimoto, Y. PY - 2007 DA - 2007// TI - Inhibition of the mitogen-activated protein kinase pathway results in the down-regulation of P-glycoprotein JO - Mol Cancer Ther VL - 6 UR - https://doi.org/10.1158/1535-7163.MCT-07-0148 DO - 10.1158/1535-7163.MCT-07-0148 ID - Katayama2007 ER - TY - JOUR AU - Yun, J. AU - Rago, C. AU - Cheong, I. AU - Paglierini, R. AU - Angenendt, P. AU - Rajagopalan, H. AU - Schmidt, K. AU - Willson, J. K. AU - Markowitz, S. AU - Zhou, S. AU - Diaz, L. A. AU - Velculescu, V. E. AU - Lengauer, C. AU - Kinzler, K. W. AU - Vogelstein, B. AU - Papadopoulos, N. PY - 2009 DA - 2009// TI - Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells JO - Science VL - 325 UR - https://doi.org/10.1126/science.1174229 DO - 10.1126/science.1174229 ID - Yun2009 ER - TY - JOUR AU - Greatrix, B. W. AU - Van Vuuren, H. J. PY - 2006 DA - 2006// TI - Expression of the HXT13, HXT15 and HXT17 genes in Saccharomyces cerevisiae and stabilization of the HXT1 gene transcript by sugar-induced osmotic stress JO - Curr Genet VL - 49 UR - https://doi.org/10.1007/s00294-005-0046-x DO - 10.1007/s00294-005-0046-x ID - Greatrix2006 ER - TY - JOUR AU - Nourani, A. AU - Wesolowski-Louvel, M. AU - Delaveau, T. AU - Jacq, C. AU - Delahodde, A. PY - 1997 DA - 1997// TI - Multi-drug-resistance phenomenon in the yeast Saccharomyces cerevisiae: involvement of two hexose transporters JO - Mol Cell Biol VL - 17 UR - https://doi.org/10.1128/MCB.17.9.5453 DO - 10.1128/MCB.17.9.5453 ID - Nourani1997 ER - TY - JOUR AU - Plemper, R. K. AU - Egner, R. AU - Kuchler, K. AU - Wolf, D. H. PY - 1998 DA - 1998// TI - Endoplasmic reticulum degradation of a mutated ATP-binding cassette transporter Pdr5 proceeds in a concerted action of Sec61 and the proteasome JO - J Biol Chem VL - 273 UR - https://doi.org/10.1074/jbc.273.49.32848 DO - 10.1074/jbc.273.49.32848 ID - Plemper1998 ER - TY - JOUR AU - Egner, R. AU - Mahé, Y. AU - Pandjaitan, R. AU - Kuchler, K. PY - 1995 DA - 1995// TI - Endocytosis and vacuolar degradation of the plasma membrane-localized Pdr5 ATP-binding cassette multidrug transporter in Saccharomyces cerevisiae JO - Mol Cell Biol VL - 15 UR - https://doi.org/10.1128/MCB.15.11.5879 DO - 10.1128/MCB.15.11.5879 ID - Egner1995 ER - TY - JOUR AU - Cameroni, E. AU - Hulo, N. AU - Roosen, J. AU - Winderickx, J. AU - De Virgilio, C. PY - 2004 DA - 2004// TI - The novel yeast PAS kinase Rim 15 orchestrates G0-associated antioxidant defense mechanisms JO - Cell cycle VL - 3 UR - https://doi.org/10.4161/cc.3.4.791 DO - 10.4161/cc.3.4.791 ID - Cameroni2004 ER - TY - JOUR AU - Wei, M. AU - Fabrizio, P. AU - Hu, J. AU - Ge, H. AU - Cheng, C. AU - Li, L. AU - Longo, V. D. PY - 2008 DA - 2008// TI - Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9 JO - PLoS Genet VL - 4 UR - https://doi.org/10.1371/journal.pgen.0040013 DO - 10.1371/journal.pgen.0040013 ID - Wei2008 ER - TY - JOUR AU - Powers, T. PY - 2007 DA - 2007// TI - TOR Signaling and S6 Kinase 1: Yeast Catches Up JO - Cell Metabolism VL - 6 UR - https://doi.org/10.1016/j.cmet.2007.06.009 DO - 10.1016/j.cmet.2007.06.009 ID - Powers2007 ER - TY - JOUR AU - Urban, J. AU - Soulard, A. AU - Huber, A. AU - Lippman, S. AU - Mukhopadhyay, D. AU - Deloche, O. AU - Wanke, V. AU - Anrather, D. AU - Ammerer, G. AU - Riezman, H. AU - Broach, J. R. AU - De Virgilio, C. AU - Hall, M. N. AU - Loewith, R. PY - 2007 DA - 2007// TI - Sch9 is a major target of TORC1 in Saccharomyces cerevisiae JO - Mol Cell VL - 26 UR - https://doi.org/10.1016/j.molcel.2007.04.020 DO - 10.1016/j.molcel.2007.04.020 ID - Urban2007 ER - TY - JOUR AU - Karbowniczek, M. AU - Spittle, C. S. AU - Morrison, T. AU - Wu, H. AU - Henske, E. P. PY - 2008 DA - 2008// TI - mTOR is activated in the majority of malignant melanomas JO - J Invest Dermatol VL - 128 UR - https://doi.org/10.1038/sj.jid.5701074 DO - 10.1038/sj.jid.5701074 ID - Karbowniczek2008 ER - TY - JOUR AU - Basso, A. D. AU - Mirza, A. AU - Liu, G. AU - Long, B. J. AU - Bishop, W. R. AU - Kirschmeier, P. PY - 2005 DA - 2005// TI - The Farnesyl Transferase Inhibitor (FTI) SCH66336 (lonafarnib) inhibits Rheb farnesylation and mTOR signaling. Role in FTI enhancement of taxane and tamoxifen anti-tumor activity JO - J Biol Chem VL - 280 UR - https://doi.org/10.1074/jbc.M503763200 DO - 10.1074/jbc.M503763200 ID - Basso2005 ER - TY - JOUR AU - Fox, G. C. AU - Shafiq, M. AU - Briggs, D. C. AU - Knowles, P. P. AU - Collister, M. AU - Didmon, M. J. AU - Makrantoni, V. AU - Dickinson, R. J. AU - Hanrahan, S. AU - Totty, N. AU - Stark, M. J. R. AU - Keyse, S. M. AU - McDonald, N. Q. PY - 2007 DA - 2007// TI - Redox-mediated substrate recognition by Sdp1 defines a new group of tyrosine phosphatases JO - Nature VL - 447 UR - https://doi.org/10.1038/nature05804 DO - 10.1038/nature05804 ID - Fox2007 ER - TY - JOUR AU - Chen, R. E. AU - Thorner, J. PY - 2007 DA - 2007// TI - Function and regulation in MAPK signaling pathways: lessons learned from the yeast Saccharomyces cerevisiae JO - Biochim Biophys Acta VL - 1773 UR - https://doi.org/10.1016/j.bbamcr.2007.05.003 DO - 10.1016/j.bbamcr.2007.05.003 ID - Chen2007 ER - TY - JOUR AU - Hahn, J. S. AU - Thiele, D. J. PY - 2002 DA - 2002// TI - Regulation of the Saccharomyces cerevisiae Slt2 kinase pathway by the stress-inducible Sdp1 dual specificity phosphatase JO - J Biol Chem VL - 277 UR - https://doi.org/10.1074/jbc.M202557200 DO - 10.1074/jbc.M202557200 ID - Hahn2002 ER - TY - JOUR AU - Heymont, J. AU - Berenfeld, L. AU - Collins, J. AU - Kaganovich, A. AU - Maynes, B. AU - Moulin, A. AU - Ratskovskaya, I. AU - Poon, P. P. AU - Johnston, G. C. AU - Kamenetsky, M. AU - DeSilva, J. AU - Sun, H. AU - Petsko, G. A. AU - Engebrecht, J. PY - 2000 DA - 2000// TI - TEP1, the yeast homolog of the human tumor suppressor gene PTEN/MMAC1/TEP1, is linked to the phosphatidylinositol pathway and plays a role in the developmental process of sporulation JO - Proc Natl Acad Sci USA VL - 97 UR - https://doi.org/10.1073/pnas.97.23.12672 DO - 10.1073/pnas.97.23.12672 ID - Heymont2000 ER - TY - JOUR AU - Schmidt, A. AU - Schmelzle, T. AU - Hall, M. N. PY - 2002 DA - 2002// TI - The RHO1-GAPs SAC7, BEM2 and BAG7 control distinct RHO1 functions in Saccharomyces cerevisiae JO - Mol Microbiol VL - 45 UR - https://doi.org/10.1046/j.1365-2958.2002.03110.x DO - 10.1046/j.1365-2958.2002.03110.x ID - Schmidt2002 ER - TY - JOUR AU - Durkin, M. E. AU - Yuan, B. Z. AU - Zhou, X. AU - Zimonjic, D. B. AU - Lowy, D. R. AU - Thorgeirsson, S. S. AU - Popescu, N. C. PY - 2007 DA - 2007// TI - DLC-1:a Rho GTPase-activating protein and tumour suppressor JO - J Cell Mol Med VL - 11 UR - https://doi.org/10.1111/j.1582-4934.2007.00098.x DO - 10.1111/j.1582-4934.2007.00098.x ID - Durkin2007 ER - TY - JOUR AU - Francisco, L. AU - Chan, C. S. PY - 1994 DA - 1994// TI - Regulation of yeast chromosome segregation by Ipl1 protein kinase and type 1 protein phosphatase JO - Cell Mol Biol Res VL - 40 ID - Francisco1994 ER - TY - JOUR AU - Tanaka, M. AU - Ueda, A. AU - Kanamori, H. AU - Ideguchi, H. AU - Yang, J. AU - Kitajima, S. AU - Ishigatsubo, Y. PY - 2002 DA - 2002// TI - Cell-cycle-dependent regulation of human aurora A transcription is mediated by periodic repression of E4TF1 JO - J Biol Chem VL - 277 UR - https://doi.org/10.1074/jbc.M108252200 DO - 10.1074/jbc.M108252200 ID - Tanaka2002 ER - TY - JOUR AU - Sepp-Lorenzino, L. AU - Ma, Z. AU - Rands, E. AU - Kohl, N. E. AU - Gibbs, J. B. AU - Oliff, A. AU - Rosen, N. PY - 1995 DA - 1995// TI - A peptidomimetic inhibitor of Farnesyl:protein transferase blocks the anchorage-dependent and -independent growth of human tumor cell lines JO - Cancer Res VL - 55 ID - Sepp-Lorenzino1995 ER - TY - JOUR AU - Medeiros, B. C. AU - Landau, H. J. AU - Morrow, M. AU - Lockerbie, R. O. AU - Pitts, T. AU - Eckardt, S. G. PY - 2007 DA - 2007// TI - The farnesyl transferase inhibitor, tipifarnib, is a potent inhibitor of the MDR1 gene product, P-glycoprotein, and demonstrates significant cytotoxic synergism against human leukemia cell lines JO - Leukemia VL - 21 ID - Medeiros2007 ER - TY - JOUR AU - Wagner, W. AU - Bielli, P. AU - Wacha, S. AU - Ragnini-Wilson, A. PY - 2002 DA - 2002// TI - Mlc1p promotes septum closure during cytokinesis via the IQ motifs of the vesicle motor Myo2p JO - EMBO J VL - 21 UR - https://doi.org/10.1093/emboj/cdf650 DO - 10.1093/emboj/cdf650 ID - Wagner2002 ER - TY - JOUR AU - Bielli, P. AU - Casavola, E. C. AU - Biroccio, A. AU - Urbani, A. AU - Ragnini-Wilson, A. PY - 2006 DA - 2006// TI - GTP drives myosin light chain 1 interaction with the class V myosin Myo2 IQ motifs via a Sec2 RabGEF-mediated pathway JO - Mol Microbiol VL - 59 UR - https://doi.org/10.1111/j.1365-2958.2006.05041.x DO - 10.1111/j.1365-2958.2006.05041.x ID - Bielli2006 ER - TY - CHAP AU - Ausubel, F. M. AU - Brent, R. AU - Kingston, R. E. AU - Moore, D. D. AU - Seidman, J. G. AU - Smith, J. A. AU - Struhl, K. PY - 1994 DA - 1994// TI - Preparation of yeast RNA BT - Current Protocols in Molecular Biology ID - Ausubel1994 ER - TY - JOUR AU - Bialek-Wyrzykowska, U. AU - Bauer, B. E. AU - Wagner, W. AU - Kohlwein, S. D. AU - Schweyen, R. J. AU - Ragnini, A. PY - 2000 DA - 2000// TI - Low levels of Ypt protein prenylation cause vesicle polarization defects and thermosensitive growth that can be suppressed by genes involved in cell wall maintenance JO - Mol Microbiol VL - 35 UR - https://doi.org/10.1046/j.1365-2958.2000.01782.x DO - 10.1046/j.1365-2958.2000.01782.x ID - Bialek-Wyrzykowska2000 ER -