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Table 3 TRAIL-R1 expression: Cox regression analysis for overall survival of patients with colorectal carcinoma

From: Prognostic significance of TRAIL death receptors in Middle Eastern colorectal carcinomas and their correlation to oncogenic KRAS alterations

 

UNIVARIATE

MULTIVARIATE

Clinical Parameters

Risk Ratio (95% CI)

p value

Risk Ratio (95% CI)

p value

Age: Above = 50

1.17 (0.80-1.74)

0.4306

1.40 (0.86 - 2.33)

0.1755

Sex: Male

1.10 (0.76-1.59)

0.6084

1.18 (0.75 - 1.87)

0.4589

Stage: III-IV

7.26 (4.34-13.03)

< 0.0001

6.56 (3.67 - 12.78)

< 0.0001

Grade: Poorly differentiated

1.41 (0.90-2.14)

0.1307

3.61 (1.72 - 6.80)

0.0014

MSI status: MSI-L/S

2.04 (1.14 - 4.05)

0.0149

1.90 (0.95 - 4.37)

0.0713

Histology: Adenocarcinoma

1.14 (0.67 - 2.10)

0.6499

2.28 (0.93 - 5.43)

0.0695

TRAIL-R1: Low expression

1.18 (1.11 - 2.83)

0.0196

1.84 (1.10 - 3.02)

0.0273

  1. CI = confidence interval