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Figure 3 | Molecular Cancer

Figure 3

From: The Wnt/β-catenin pathway regulates growth and maintenance of colonospheres

Figure 3

Differentiation and proliferation potential of parental colon cancer cells and the corresponding spheroids/colonospheres. A. Spheroids show decreased alkaline phosphatase activity compared to parental colon cancer cells. B. Induction of alkaline phosphatase activity in the spheroids in response to Na-butyrate. C. Changes in cellular growth of parental cell lines and colonospheres over the period of 5 days as determined by MTT assay. Each value represents mean ± SD of six observations. *p < 0.001, compared to the corresponding parental cells or control.

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