Figure 3From: A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cellsStattic (reported STAT3 inhibitor) and WP1066 (reported JAK2 inhibitor) were able to inhibit STAT3 phosphorylation and induce apoptosis indicated by increased cleaveage of capase-3 in (A) HCT116 colon cancer and (B) U266 multiple myeloma cells.Back to article page