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Table 1 Gene targets identified by RNAi screening as important in growth of Ewing's sarcoma cells.

From: RNAi phenotype profiling of kinases identifies potential therapeutic targets in Ewing's sarcoma

Gene Symbol Entrez Gene # Gene Name
AKAP3 10566 A kinase (PRKA) anchor protein 3
AKT1 207 v-akt murine thymoma viral oncogene homolog 1
CDK5R2 8941 cyclin-dependent kinase 5, regulatory subunit 2
GRK4 2868 G protein-coupled receptor kinase 4
MAST1 22983 microtubule associated serine/threonine kinase 1
MK-STYX 51657 STYXL1 serine/threonine/tyrosine interacting-like 1
NEK3 4752 NIMA (never in mitosis gene a)-related kinase 3
NEK9 91754 NIMA (never in mitosis gene a)- related kinase 9
NTRK3 4916 neurotrophic tyrosine kinase, receptor, type 3
PIK3AP1 118788 phosphoinositide-3-kinase adaptor protein 1
PRKCA 5578 protein kinase C, alpha
PXK 54899 PX domain containing serine/threonine kinase
STK10* 6793 serine/threonine kinase 10
STK11 6794 serine/threonine kinase 11
TAOK3 51347 TAO kinase 3
TNK2 10188 tyrosine kinase, non-receptor, 2
  1. *Both the siRNAs for this gene showed significant growth inhibition.