Table 1 Gene targets identified by RNAi screening as important in growth of Ewing's sarcoma cells.
From: RNAi phenotype profiling of kinases identifies potential therapeutic targets in Ewing's sarcoma
Gene Symbol | Entrez Gene # | Gene Name |
|---|---|---|
AKAP3 | 10566 | A kinase (PRKA) anchor protein 3 |
AKT1 | 207 | v-akt murine thymoma viral oncogene homolog 1 |
CDK5R2 | 8941 | cyclin-dependent kinase 5, regulatory subunit 2 |
GRK4 | 2868 | G protein-coupled receptor kinase 4 |
MAST1 | 22983 | microtubule associated serine/threonine kinase 1 |
MK-STYX | 51657 | STYXL1 serine/threonine/tyrosine interacting-like 1 |
NEK3 | 4752 | NIMA (never in mitosis gene a)-related kinase 3 |
NEK9 | 91754 | NIMA (never in mitosis gene a)- related kinase 9 |
NTRK3 | 4916 | neurotrophic tyrosine kinase, receptor, type 3 |
PIK3AP1 | 118788 | phosphoinositide-3-kinase adaptor protein 1 |
PRKCA | 5578 | protein kinase C, alpha |
PXK | 54899 | PX domain containing serine/threonine kinase |
STK10* | 6793 | serine/threonine kinase 10 |
STK11 | 6794 | serine/threonine kinase 11 |
TAOK3 | 51347 | TAO kinase 3 |
TNK2 | 10188 | tyrosine kinase, non-receptor, 2 |