Figure 3From: Effects of nilotinib on regulatory T cells: the dose mattersNilotinib does not induce apoptosis on CD4+CD25+ T cells and CD4+CD25-T cells. CD4+CD25+ T cells (Panel A) and CD4+CD25-T cells (Panel B) were stimulated with anti-CD3, anti-CD28 and IL-2 with different concentrations of nilotinib as indicated for 48 h. Cells were then harvested and stained with Annexin V* FITC and PI. Apoptotic cells were defined by flow cytometry as Annexin V positive and PI negative cells.Back to article page