Skip to main content
Figure 2 | Molecular Cancer

Figure 2

From: Gefitinib radiosensitizes non-small cell lung cancer cells through inhibition of ataxia telangiectasia mutated

Figure 2

Multinuclei formation after the treatment with gefitinib plus ionizing radiation (IR) in lung cancer cells. A, Nuclear morphology of NCI-H460 (upper), VMRC-LCD (middle), and A549 (bottom) cells after the gefitinib plus IR treatment. Cells were grown on coverslips and treated with 15 μmol/L gefitinib for 48 h, and then irradiated with 6 Gy IR. After the indicated times, cells were fixed, stained with DAPI, and then observed under confocal microscopy (X400 magnification). Multinucleated cells were indicated with arrow. B, The number of multinucleated cells was counted and plotted. At least 100 cells per sample were counted. Each columns represent the means of three independent experiments; Error bars, SE.

Back to article page