Figure 4
From: A Pleiotrophin C-terminus peptide induces anti-cancer effects through RPTPβ/ζ
Elucidation of the mechanism through which P(122-131) exerts its biological actions. Effect of P(122-131) on adhesion (A), anchorage-independent proliferation (B), and migration (C) of DU145, DU145-HM2, and DU145-RM6 cells. DU145-HM2 cells transfected with pleiotrophin antisense RNA, DU145-RM6 cells transfected with shRNA targeting RPTPβ/ζ. The last two bars of each diagram indicate DU145-HM2 cells that were transiently transfected with siRNA targeting RPTPβ/ζ. Results are mean values ± SE from at least 3 independent experiments.