Figure 5
From: A Pleiotrophin C-terminus peptide induces anti-cancer effects through RPTPβ/ζ
Src, Fak, and Erk1/ 2 are inactivated by P(122-131), while PTEN is activated. Western blot analysis of phosphorylated Src(A), Fak (B) Pten (C), and Erk1/2 (D), in cells stimulated with increasing concentrations of P(122-131) for 3, 15, and 45 minutes. The blots were stripped and reprobed for HSC70. Results are expressed as % change relative to control and are mean values ± SE from at least 3 independent experiments.