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Table 3 Results of univariate analysis for factors associated with advanced HCC stage at diagnosis

From: Role of microRNA-199a-5p and discoidin domain receptor 1 in human hepatocellular carcinoma invasion

Variable AJCC/UICC stage I-II AJCC/UICC stage III-IV p value
Male gender 66.7% 71.4% 0.80
Age (years) 69.4 ± 8.0 60 ± 18.1 0.20
Multiple tumor nodules 44.4% 42.9% 0.94
Diameter of the biggest nodule (cm) 6.7 ± 4.4 9.8 ± 4.0 0.10
Viral infection 22.2% 28.6% 0.73
Cirrhosis 44.4% 28.6% 0.43
Poorly differentiated HCC (G4) 0% 50% 0.01
Macrovascular invasion 22.2% 64.3% 0.04
Mir-199a expression (median value) 0.07 0.36 0.17
DDR1 expression (median value) 1.54 5.05 0.01