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Figure 1 | Molecular Cancer

Figure 1

From: I-kappa-kinase-2 (IKK-2) inhibition potentiates vincristine cytotoxicity in non-Hodgkin's lymphoma

Figure 1

ML120B inhibits cell growth, cell cycle progression and phosphorylation of IκBα in Lymphoma cell lines. A. IC50 was calculated by trypan blue exclusion assay for each cell line after 48 h incubation. Cell number (vertical axis) = Mean and SEM [standard error of mean]. B. DNA content was analyzed by PI staining using flow cytometry after 48 h for each cell line. C. Lymphoma cell lines were cultured for 60 minutes with ML120B at the indicated concentrations and whole cell lysates were subjected to Western blot for detection of p-IκBα, IκBα and actin (Arrows indicate total IκBα).

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