Figure 5
From: MiR-221 and miR-222 target PUMA to induce cell survival in glioblastoma
MiR-221/222 inversely correlate with PUMA expression in glioma tissues. (A) Expression of miR-221/222 and PUMA was analyzed in representative of gliomas with LNA-ISH and immunohistochemical staining. Expression levels of miR-221/222 and PUMA were quantified as described in methods. (B) Chisquare test analysis of miR-221/222 and PUMA expression. The inverse correlation is significant (p < 0.001).