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Table 6 Summary of the most relevant gene sets enriched in responders and non-responders to chemotherapy

From: An ANOCEF genomic and transcriptomic microarray study of the response to radiotherapy or to alkylating first-line chemotherapy in glioblastoma patients

Gene sets most significantly enriched in responders

BH adjusted

p-value

Gene sets most significantly enriched in non-responders

BH adjusted p-value

MSigDB C2 pathways AGEING_BRAIN_UP

< 10-4

SMD chromArms 9p

0.005

SMD cancerModules CNS genes

< 10-4

MSigDB C2 pathways STEMCELL_NEURAL_UP

0.007

Murat et al. normal brain gene cluster (G18)

< 10-4

MSigDB C2 pathways LEE_TCELLS2_UP

0.01

SMD tissues Brain_sw

0.06

GO:0001952 - regulation of cell-matrix adhesion

0.02

  

MSigDB C2 pathways STEMCELL_EMBRYONIC_UP

Murat et al. stem cell gene cluster (G28_G98)

0.02

1

  1. Summary of gene sets analysis using KEGG, Biocarta pathways, Gene Ontology (GO) terms, Molecular Signatures Database (MSigDB) gene sets and Stanford microarray database (SMD) and Murat et al.'s gene sets [12]. BH: Benjamini and Hochberg.
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Molecular Cancer

ISSN: 1476-4598