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Figure 6 | Molecular Cancer

Figure 6

From: ErbB2 enhances mammary tumorigenesis, oncogene-independent recurrence and metastasis in a model of IGF-IR-mediated mammary tumorigenesis

Figure 6

Metastatic lesions from MTB-IGFIR transgenic mice display elevated ErbB2 expression. Representative ErbB2 staining in lung sections (a, b, c) and primary tumors (d, e, f); LM denotes the metastatic lung lesion, while NL refers to surrounding normal lung tissue. Quantitative analysis revealed that an approximate 2-fold higher level of positivity (p = 0.15) and a 30-fold increase in strong positive labeled cells (p = 0.16) in metastases compared to primary tumors (g).

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