Figure 2From: Prognostic significance and therapeutic implications of centromere protein F expression in human nasopharyngeal carcinomaExpression analysis of CENP-F mRNA and protein in NPC samples. A. Real-time RT-PCR analysis of CENP-F mRNA in normal nasopharyngeal biopsies (Normal) and nasopharyngeal carcinoma biopsies (NPC). B-F. Immunohistochemistry analysis of CENP-F expression in archived NPC tissue. CENP-F specific expression is observed in tumor cells and not in the uninvolved nasopharyngeal epithelia (B). CENP-F is not expressed in normal epithelial cells (C). CENP-F expression was mainly localized within nuclei of cancer cells (D, E and F), and its expression was observed mainly in the invasive front areas (E and F). B (×100), E (×200) and C, D, F (×400).Back to article page