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Figure 10 | Molecular Cancer

Figure 10

From: Epstein-Barr virus-encoded EBNA1 enhances RNA polymerase III-dependent EBER expression through induction of EBER-associated cellular transcription factors

Figure 10

TFIIIC-102 is upregulated in EBV-positive NPC tumour cells. Serial sections of an NPC biopsy were (A) stained with haematoxylin and eosin; (B) shown to contain strongly EBER-positive tumour cells by in situ hybridisation; (C) strongly positive for TFIIIC-102 compared with the surrounding stromal, non-tumour cells. (D) Shows similar staining in a different biopsy. (E) Levels of mRNA for TFIIIC-102 in tumour tissue compared with normal epithelium.

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