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Figure 3 | Molecular Cancer

Figure 3

From: Epstein-Barr virus-encoded EBNA1 enhances RNA polymerase III-dependent EBER expression through induction of EBER-associated cellular transcription factors

Figure 3

EBNA1 induces TFIIIC genes, but not TFIIIB transcripts in Ad/AH, AGS, and HONE-1 cells. Levels of transcripts were assayed using RT-qPCR in epithelial cell lines expressing neomycin control plasmids or EBNA1. For comparative purposes, EBV-infected Ad/AH cells are included. Fold change values are between neo control cells and EBNA1-expressing or EBV-infected cells, as appropriate. All data are means of three biological replicates analysed in technical triplicate. Error bars represent the standard deviation in fold change between biological replicates. Asterisks indicate that the fold change between neo control and EBNA1-transfected or EBV-positive cells is statistically significant. *, P ≤ 0.05; **, P ≤ 0.01.

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