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Figure 9 | Molecular Cancer

Figure 9

From: Epstein-Barr virus-encoded EBNA1 enhances RNA polymerase III-dependent EBER expression through induction of EBER-associated cellular transcription factors

Figure 9

ATF-2 and c-Myc induction is significant in regulating EBER expression. RT-PCR was used to assay (a) EBER expression following transient shRNA knock-down of ATF-2; (b) EBER expression following transient shRNA knock-down of c-Myc; (c) EBER expression following tamoxifen induction of c-MycER in Ad/AH-EBERs cells; (d) EBER expression following tamoxifen induction of c-MycER in Ad/AH ΔX EBER cells with the c-Myc binding site (X-box upstream of EBER1) excised. Numbers to the right of the gel images indicate the mean fold change (± SD) of expression in triplicate experiments.

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