Figure 9From: Epstein-Barr virus-encoded EBNA1 enhances RNA polymerase III-dependent EBER expression through induction of EBER-associated cellular transcription factorsATF-2 and c-Myc induction is significant in regulating EBER expression. RT-PCR was used to assay (a) EBER expression following transient shRNA knock-down of ATF-2; (b) EBER expression following transient shRNA knock-down of c-Myc; (c) EBER expression following tamoxifen induction of c-MycER in Ad/AH-EBERs cells; (d) EBER expression following tamoxifen induction of c-MycER in Ad/AH ΔX EBER cells with the c-Myc binding site (X-box upstream of EBER1) excised. Numbers to the right of the gel images indicate the mean fold change (± SD) of expression in triplicate experiments.Back to article page