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Figure 10 | Molecular Cancer

Figure 10

From: Axin downregulates TCF-4 transcription via β-catenin, but not p53, and inhibits the proliferation and invasion of lung cancer cells

Figure 10

Expression of various Axin constructs decreases the invasive ability of BE1 and A549 cells. Cells were seeded on the upper chamber (5 × 104 cells/well) 24 h after transfection and incubated for 48 h. (A&C) A representative microscope field of filters under the Matrigel from BE1 and A549, respectively. (B&D) Quantification of the number of migrated BE1 and A549 cells, respectively. * P < 0.05, ** P < 0.01.

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