Figure 2From: Axin downregulates TCF-4 transcription via β-catenin, but not p53, and inhibits the proliferation and invasion of lung cancer cellsThe composition and expression of Axin mutants. (A) Schematic representation of the mutants of the Axin mutants used in this study. The binding sites for HIPK2, β-catenin and p53 are indicated. (B) BE1 cells were transfected with the indicated EGFP-tagged Axin construct. Total cell lysates were resolved by SDS-PAGE and Western blot analysis was performed using anti-EGFP antibody to detect the expression of the different Axin mutants.Back to article page