From: Multiple functions of CXCL12 in a syngeneic model of breast cancer
Strain | Experiment | Day terminated | Mean tumor weight (g) ± SEM (n) | p value (t test) | 4TX12 tumor weight as% of control | |
---|---|---|---|---|---|---|
 |  |  | 4T12Ala | 4TX12 |  |  |
Wild type | 1 | 33 | 0.83 ± 0.06 (12) | 0.20 ± 0.04 (12) | ***, <0.0001 | 24.2 |
 | 2 | 27 | 0.90 ± 0.13 (5) | 0.21 ± 0.07 (6) | ***, 0.0008 | 22.9 |
SCID | 1 | 19 | 0.56 ± 0.11 (5) | 0.60 ± 0.02 (5) | ns, 0.7426 | 106.6 |
 | 2 | 23 | 0.79 ± 0.08 (5) | 0.76 ± 0.06 (5) | ns, 0.7236 | 95.4 |
pfp-/- | 1 | 28 | 0.79 ± 0.10 (6) | 0.49 ± 0.05 (6) | *, 0.0232 | 61.4 |
TRAIL-/- | 1 | 28 | 0.78 ± 0.14 (7) | 0.44 ± 0.03 (7) | *, 0.0369 | 57.1 |
IFN-γ-/- | 1 | 28 | 1.21 ± 0.17 (7) | 0.64 ± 0.18 (7) | *, 0.0403 | 52.9 |