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Figure 4 | Molecular Cancer

Figure 4

From: Salirasib inhibits the growth of hepatocarcinoma cell lines in vitro and tumor growth in vivo through ras and mTOR inhibition

Figure 4

Salirasib induces apoptosis in HepG2 and Hep3B cells. A-C. Caspase activity assay performed after 24 hours of treatment with the indicated doses of salirasib in HepG2 (A), Huh7 (B), and Hep3B (C). D. Representative Western blots of three independent experiments of cytochrome c after 24 hours of treatment. Data are expressed as relative change versus control (DMSO) set arbitrarily at 1 and are presented as mean ± SEM. * P < 0.05, ** P < 0.01 and *** P < 0.001 in treated groups versus control group.

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