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Table 1 Sin3A regulation of genes associated with breast cancer or estrogen receptor signaling

From: Maximum growth and survival of estrogen receptor-alpha positive breast cancer cells requires the Sin3A transcriptional repressor

Sin3A Responsive

Sin3A Non-responsive

C3

CCND1

CDH1

CCNG2

CDKN1A

HMGB1

CLU

KRT18

ERBB2

KRT19

GATA3

MAP2K7

MUC1

NCOA3

SERPINA3

NME1

ESR1*

PIN1

MYC

SERPINB9

NCOA2

TFF1

PGR

TGFA

 

TOP2A

 

TP53

  1. bold = significant (p < 0.05) increase in basal level of gene by Sin 3A siRNA
  2. bold italic= significant (p < 0.05) change in estrogen response of gene by Sin3A siRNA
  3. * = previously identified [9]