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Figure 4 | Molecular Cancer

Figure 4

From: Synergistic effect of gefitinib and rofecoxib in mesothelioma cells

Figure 4

Curves of cell proliferation after the addition simultaneously of Rofecoxib and Gefitinib. Ist-Mes-1, Ist-Mes-2 and MPP89 were treated with four different associations: 25 μM gefitinib+4 μM rofecoxib, 25 μM gefitinib+12 μMrofecoxib, 25 μM gefitinib+36 μMrofecoxib and 12 μM rofecoxib+12, 5 μM gefitinib. The survival of cells after treatment with drugs alone and in combination was compared to control performed with DMSO at the same final concentration of that present in medium with drugs. Values were reported as means ± SD of three independent experiments, and asterisks indicate significant difference (P < 0.05) of the treatment with two drugs vs single drug calculated by Student's t-test.

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