From: Synergistic epigenetic reactivation of estrogen receptor-α (ERα) by combined green tea polyphenol and histone deacetylase inhibitor in ERα-negative breast cancer cells
Cells
Percentage of methylated CpG island in the ER promoter (%)
P value compared with untreated MDA-MB-231 cells
MCF-7
0
-
Untreated MDA-MB-231
44.8 ± 3.75*
EGCG-treated MDA-MB-231
48.2 ± 4.45*
0.36