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Table 1 List of genes in the p53-p21 pathway downregulated following Sp1 knockdown

From: Sp1 acetylation is associated with loss of DNA binding at promoters associated with cell cycle arrest and cell death in a colon cell line

Probe Set ID Gene Title Gene Symbol 48 hr post Sp1 knockdown 72 hr post Sp1 knockdown
    Fold change Regulation Fold change Regulation
1556990_at PERP, TP53 apoptosis effector PERP 2.87 down 2.46 down
211725_s_at BH3 interacting domain death agonist BID 1.78 down 1.85 down
227143_s_at BH3 interacting domain death agonist BID 1.64 down 1.70 down
204493_at BH3 interacting domain death agonist BID 1.82 down - No change
209644_x_at cyclin-dependent kinase inhibitor 2A (p16) CDKN2A (p14ARF) 1.53 down 1.51 down
207039_at cyclin-dependent kinase inhibitor 2A (p16) CDKN2A (p14ARF) 1.58 down - No change
224851_at cyclin-dependent kinase 6 CDK6 1.40 down - No change
209305_s_at growth arrest and DNA-damage-inducible, beta GADD45B 1.31 down - No change
214710_s_at cyclin B1 CCNB1 1.30 down - No change
204315_s_at G-2 and S-phase expressed 1 GTSE1 (B99) 1.23 down - No change
218424_s_at STEAP family member 3 STEAP3 (TSAP6) 1.22 down - No change
236814_at Mdm4, transformed 3T3 cell double minute 4, p53 binding protein (mouse) MDM4 1.73 down - No change
225740_x_at Mdm4, transformed 3T3 cell double minute 4, p53 binding protein (mouse) MDM4 - No change 1.74 down
202763_at caspase 3, apoptosis-related cysteine peptidase CASP3 - No change 1.29 down