Figure 7From: Butyrate suppresses expression of neuropilin I in colorectal cell lines through inhibition of Sp1 transactivationModel for regulation of NRP-1 expression by Sp transcription factors and HDACs. The model shows the interaction between Sp1, Sp3S and Sp3L function in the presence and absence of HDAC inhibition and also accounts for the effects of knockdown of Sp1 or Sp3 using the siRNA strategy.Back to article page