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Figure 4 | Molecular Cancer

Figure 4

From: Dasatinib reduces FAK phosphorylation increasing the effects of RPI-1 inhibition in a RET/PTC1-expressing cell line

Figure 4

Phosphotyrosine protein separation of TPC-1 cells before and after drug treatments. (A) anti-p-Tyr immunoblot of equal amounts of TPC-1 whole-cell extracts from control (0.5% solvent), or cells treated with RPI-1 (40 μM), dasatinib (100 nM), or both, resolved by 4-12% SDS-PAGE. (B) Effects of RPI-1 and dasatinib treatments (used alone or in combination) on the anti-p-Tyr immunoprecipitates from TPC-1 cells, anti-p-Tyr immunostained and resolved by 3-8% SDS-PAGE.

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Molecular Cancer

ISSN: 1476-4598