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Figure 4 | Molecular Cancer

Figure 4

From: An evolved ribosome-inactivating protein targets and kills human melanoma cells in vitro and in vivo

Figure 4

Binding of 125I-SLT-1AIYSNKLM to 518-A2 cells. (A) Specific binding (white squares), total binding (black squares), and non-specific binding (white triangles) of 125I-SLT-1AIYSNKLM to 518-A2 cells at 4Ā°C. (B) Displacement curves in which 518-A2 cells were treated with 45 nM of 125I-SLT-1AIYSNKLM in the presence of increasing concentrations of either unlabeled SLT-1AIYSNKLM (black circles) or a synthetic 16-residue peptide containing the inserted 7-amino acid peptide ligand (HHHIYSNKLM ASRVAR) (black squares). Data points represent the s.e.m. of experiments performed in triplicate.

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