Table 1 Clinico-pathological characteristics and HPV status of cervical biopsies from normal control tissues and from cervical precancer and cancer lesions
Tissue type | Characteristics | Number of samples | Total HPV+ (HPV L1) | HPV 16+ (% positivity) | Mean age (Years; ± SD) |
|---|---|---|---|---|---|
Normal controls | Â | 20 | 0 | 0 | Â |
|  | Normal cervical tissues without inflammation | 15 | 0 | 0 | 25 ± 4.6 |
|  | Normal cervical tissues with inflammation | 5 | 0 | 0 | 31 ± 3.5 |
Precancer |  | 30 | 17 | 16 (53%) | 29 ± 3.5 |
| Â | Low grade squamous intraepithelial lesions | 15 | 7 | 7 (47%) | Â |
| Â | High grade squamous intraepithelial lesions | 15 | 10 | 9 (60%) | Â |
Cancer Tissues |  | 70 | 65 | 58 (83%) | 50 ± 12.6 |
Histopathological grading | Well Differentiated SCC | 35 | 32 | 30 (86%) | Â |
| Â | Moderately Differentiated SCC | 25 | 23 | 20 (80%) | Â |
| Â | Poorly Differentiated SCC | 10 | 10 | 8 (80%) | Â |
Clinical stages | Stage I | 08 | 06 | 05 (63%) | Â |
| Â | Stage II | 18 | 15 | 13 (72%) | Â |
| Â | Stage III | 32 | 32 | 30 (94%) | Â |
| Â | Stage IV | 12 | 12 | 10 (83%) | Â |