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Table 1 Clinico-pathological characteristics and HPV status of cervical biopsies from normal control tissues and from cervical precancer and cancer lesions

From: Aberrant expression and constitutive activation of STAT3 in cervical carcinogenesis: implications in high-risk human papillomavirus infection

Tissue type Characteristics Number of samples Total HPV+ (HPV L1) HPV 16+ (% positivity) Mean age (Years; ± SD)
Normal controls   20 0 0  
  Normal cervical tissues without inflammation 15 0 0 25 ± 4.6
  Normal cervical tissues with inflammation 5 0 0 31 ± 3.5
Precancer   30 17 16 (53%) 29 ± 3.5
  Low grade squamous intraepithelial lesions 15 7 7 (47%)  
  High grade squamous intraepithelial lesions 15 10 9 (60%)  
Cancer Tissues   70 65 58 (83%) 50 ± 12.6
Histopathological grading Well Differentiated SCC 35 32 30 (86%)  
  Moderately Differentiated SCC 25 23 20 (80%)  
  Poorly Differentiated SCC 10 10 8 (80%)  
Clinical stages Stage I 08 06 05 (63%)  
  Stage II 18 15 13 (72%)  
  Stage III 32 32 30 (94%)  
  Stage IV 12 12 10 (83%)  
  1. HPV - Human papillomavirus, SCC - Squamous cell carcinoma