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Figure 2 | Molecular Cancer

Figure 2

From: Influence of wild-type MLL on glucocorticoid sensitivity and response to DNA-damage in pediatric acute lymphoblastic leukemia

Figure 2

Reduced MLL expression is associated with GC resistance and relapse in T-ALL patients. Published HG-U133A microarray datasets were examined for the expression of MLL using either a single probe (212079_s_at) or the median of all five MLL probe sets on the array. Data represent the mean ± SEM (linear scale) of the indicated patient numbers (n). (A) Difference in MLL expression in pediatric T-ALL patient specimens with ex vivo sensitivity or resistance to prednisolone [17]; (B) Difference in MLL expression in pediatric T-ALL patient specimens measured at diagnosis or relapse [14].

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