Gene Set | Description of Network Hub Genes and Associated Functions | FDR * |
---|---|---|
MORF_PRDX3 | Peroxiredoxin 3 - MYC-mediated proliferation, glucose responses | 0.132 |
MORF_SOD1 | Superoxide dismutase 1 - mitochondria, oxidative metabolism | 0.135 |
MORF_MAP2K2 | MAP2K2 - ERK, JNK, p38, NFkB, and apoptosis pathways | 0.138 |
MORF_PTPN11 | Protein tyrosine phosphatase, cell growth, differentiation, metabolism | 0.140 |
GNF2_RAN | RAS oncogene family - cell cycle, mitotic spindle regulation | 0.143 |
MORF_GMPS | Guanine monphosphate synthetase - purine synthesis, cell cycle | 0.146 |
MORF_DEAF1 | DEAF1 or supressin, inhibitor of proliferation | 0.152 |
MORF_ERH | Enhancer of rudimentary homolog - cell cycle regulator | 0.155 |
GNF2_NS | Nucleostemin - cell cycle progression in stem cells, links with p53 | 0.158 |
MORF_GPX4 | Glutathione peroxidase 4 - cellular antioxidant defence | 0.159 |
MORF_AATF | Apoptosis antagonizing transcription factor | 0.160 |
MORF_EIF3S2 | EIF3S2 - eukaryotic translation initiation factor | 0.164 |
MORF_ATOX1 | ATX1 antioxidant protein 1 homolog - antioxidant defense | 0.165 |
MORF_EI24 | Etoposide induced mRNA - early p53 response gene | 0.166 |
MORF_PSMC1 | Proteasome 26S subunit, ATPase | 0.173 |
MORF_RAN | RAS oncogene family - cell cycle, mitotic spindle regulation | 0.179 |
MORF_RAB5A | Ras-associated protein - exocytosis, actin organisation | 0.180 |
MORF_UNG | Uracil-DNA glycosylase - base-excision DNA repair pathway | 0.182 |
MORF_FBL | Fibrillarin - component of snRNP synthesis of ribosomal RNA | 0.203 |
GCM_MAX | Myc-associated factor X - transcriptional regulator | 0.224 |