ADP-ribose polymer - a novel and general biomarker of human cancers of head & neck, breast, and cervix

Table 1 Poly-ADP-ribose adduct levels in controls and individual cancers of H & N

Category/Type/Site of cancer	Number of cases (n)	Poly-ADP-ribose adduct level (AU) (Mean ± SD)	r²	P
Control	68	14573 ±1452
All cancer of head and neck (H & N) region	66	8059 ± 304
Cancer of oesophagus	19	8007 ± 463	0.9247	< 0.0001
Cancer of alveolo	6	8173 ± 651	0.9761	< 0.0001
Cancer of pyriform sinus	4	8196 ± 258	0.9759	< 0.0001
Cancer of nasopharynx	10	7890 ± 833	0.9611	< 0.0001
Cancer of larynx	1	7537	NA	NA
Cancer of tongue	4	8340 ± 885	0.893	0.002
Cancer of tonsil	5	7879 ± 1081	0.9713	< 0.0001
Cancer of buccal mucosa	3	8172 ± 327	0.9903	< 0.0001
Cancer of pharynx	3	8177 ± 261	0.9870	< 0.0001
Cancer of lip	3	7801 ±906	0.9869	0.0066
Cancer of nasal cavity	2	8554 ± 440	NA	NA
Cancer of oral cavity	1	7681	NA	NA
Cancer of epiglottis	4	8553 ± 440	0.9849	< 0.0001
Cancer of vocal chord	1	7873	NA	NA

Table showing the analysis of unpaired t test with Welch corrections between total poly-ADP-ribose adduct level of PBL proteins (mean ± SD) in control and each site of cancer of head and neck (H & N) region. The value at each site of cancer was compared to the control separately (NA - not applicable as n was 1(single case)).

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