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Table 1 Potencies of chemotherapeutics following siRNA treatment in SKOV-3 cells.

From: Regulators of G-Protein signaling RGS10 and RGS17 regulate chemoresistance in ovarian cancer cells

  Scrambled siRNA RGS10 siRNA RGS17 siRNA RGS10 + RGS17 siRNA
Vincristine Potency (nM IC 50 +/- SEM) 5. 85 +/- 1.3 12.8 +/- 2.9 58 +/- 8.7 24 +/- 4.8
Docetaxel Potency (nM IC 50 +/- SEM) 0.886 +/- 0.432 10.7 +/- 3.7 85 +/- 23 92 +/- 25
Cisplatin Potency (μM IC 50 +/- SEM) 10.4 +/- 1.1 23.0 +/- 1.2 27.9 +/- 1.2 57.8 +/- 1.5