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Table 2 Significantly differentially expressed microRNAs in YSTs versus germinomas for adult tumours

From: The two most common histological subtypes of malignant germ cell tumour are distinguished by global microRNA profiles, associated with differential transcription factor expression

Over-expressed in YSTs

ΔΔ Ct

Adjusted p-value

Over-expressed in germinomas

ΔΔ Ct

Adjusted p-value

miR-122a

-9.98

5.66E-09

   

miR-302c*

-6.98

3.40E-08

   

miR-205

-7.34

1.20E-07

   

miR-200a

-6.57

1.85E-07

   

miR-200b

-6.33

3.76E-07

   

miR-302a

-5.81

3.76E-07

   

miR-302d

-5.75

3.76E-07

   

miR-302b*

-5.75

4.80E-07

   

miR-302b

-5.59

4.80E-07

   

miR-367

-5.56

7.35E-07

   

miR-302c

-6.43

7.99E-07

   

miR-200c

-5.49

1.23E-05

   

miR-203

-4.65

6.75E-05

   

miR-34c

-3.66

3.62E-04

   

miR-339

-3.00

3.62E-04

   

miR-144

-3.38

4.91E-04

   

miR-107

-2.71

4.91E-04

   

miR-17-5p

-3.15

1.10E-03

   

miR-34b

-3.37

1.25E-03

   

miR-106a

-3.08

1.57E-03

   

miR-133b

-2.86

6.06E-03

   

miR-338

-2.53

6.06E-03

   

miR-214

-2.10

6.06E-03

   

miR-133a

-2.73

6.46E-03

   

miR-129

-4.12

8.16E-03

   

miR-23b

-1.85

8.16E-03

   
  1. Analysis of the adult qRT-PCR data resulted in the ΔΔCt values shown. microRNAs are ranked by adjusted p-value. Members of the miR-302 cluster are shown in bold.