Figure 8From: ZNF217 confers resistance to the pro-apoptotic signals of paclitaxel and aberrant expression of Aurora-A in breast cancer cellsZNF217 overexpression is associated with altered expression of Bcl-2 family proteins. (A) Western-blot analysis of Bcl-2, Bcl-xL, Bad, Bak, Bax at basal level or (B) after 3 days of paclitaxel treatment. Histograms represent quantification of protein expression levels normalized to tubulin expression (means ± s.d. of three independent experiments). *, P < 0.05, **, P < 0.01 and ***, P < 0.001 versus the corresponding MDA-MB-231/pcDNA6 cells (Student's t-test).Back to article page