Predictive value of progression-related gene classifier in primary non-muscle invasive bladder cancer

Table 2 Correlations Between Microarray Data and RT-PCR Data for 14 Selected Genes

Prognosis related-gene Classifiers	Gene	UniGene Number	Up/down*	Correlation⁺	P ^‡
Recurrence related-gene classifier in NMIBC	MGC34830	Hs.502266	Up	0.72	< 0.001
	FANCB	Hs.554740	Up	0.62	< 0.001
	CASP8AP2	Hs.558218	Up	0.66	< 0.001
Progression related-gene classifier in NMIBC	S100A8	Hs.416073	Up	0.85	< 0.001
	CELSR3	Hs.631926	Up	0.85	< 0.001
	PFKFB4	Hs.476217	Up	0.72	< 0.001
	HMOX1	Hs.517581	Up	0.69	< 0.001
	MTAP	Hs.193268	Down	0.81	< 0.001
	MGC17624	Hs.461655	Down	0.68	< 0.001
	KIF1A	Hs.516802	Up	0.72	< 0.001
	COCH	Hs.21016	Up	0.78	< 0.001
Progression related-gene classifier in MIBC	CDH3	Hs.709226	Up	0.74	< 0.001
	DSC3	Hs.41690	Up	0.67	< 0.001
	PPP1R14C	Hs.486798	Up	0.62	< 0.001

Abbreviations: NMIBC, non-muscle invasive bladder cancer; MIBC muscle invasive bladder cancer.
* Up-regulated or down-regulated in poor prognosis group.
⁺ Correlation coefficient for microarray values versus RT-PCR values.
‡ P values for the correlation coefficients were calculated by Pearson correlation coefficient test.

ISSN: 1476-4598